If you have a general question concerning the website or any problems with download, please contact the webmaster ( lqw5322@psu.edu).
A simple tutorial for running GAMS code (i.e. file with .gms extension) is provided here.
Precursor Identifier
(2015): Identify biomass precursors that are not produced upon essential (synthetic lethal) gene deletion. (Last updated, 2016-05-26)
OptCom
(2012): A comprehensive modeling framework for the flux balance analysis of microbial communities. (Last updated, 2012-10-08)
OptForce
(2010): Identify the minimal set of genetic interventions that shape the metabolism of a microorganism. (Last updated, 2011-11-15)
SL Finder
(2009): Identify synthetic lethal genes or reactions in genome-scale metabolic models.
EMU generator
(2009): Elementary Metabolite Unit generation code for isotope mapping models. (Last updated 2014-12-01)
GrowMatch
(2009): Reconciling in silico predictions with in vivo growth observations. (Last updated 2011-07-14)
GapFind/GapFill
(2007): Identifying and filling network gaps for genome-scale metabolic models. (Last updated 2011-09-23)
FCF
(2004): Flux Coupling Analysis
OptKnock
(2003): Strain redesign for overproduction using gene/reaction deletions. (Last updated 2011-11-01)
IPRO Suite of Programs:
(2014): Integrated environment for various protein engineering tasks (Last updated, 2014-10-12)
MAPs
(2013): A database of Modular Antibody Parts for predicting and designing antibody variable domains (Last updated, 2013-05-29)
OptZyme
(2013): Enzyme redesign through the use of transition state analogues. (Last updated, 2013-05-16)
OptCDR
(2010): De novo design of antibody Complementarity Determining Regions for binding targeted epitopes in antigens.
IPRO
(2006): Iterative Protein Redesign and Optimization.
(last updated 2009-07)
eShuffle
(2001): Prediction of crossover distributions using DNA shuffling.