A simple tool to identify the biomass precursors which the microorganism is unable to synthesize upon deletion of essential, synthetic lethal (and higher order thereof) genes (reactions). This generic algorithm can be used to identify the constituent precursors to any sink metabolite the microorganism is unable to synthesize such as, biomass, lipid, cholesterol and so on.

Read the full description of the Precursor Identifier algorithm here.

Formulation: none.

Related Publications:

Chowdhury R., Chowdhury A., Maranas C.D. (2015), "Using gene essentiality and synthetic lethality information to correct yeast and CHO cell genome-scale models", Metabolites, 5(4):536-570. PMID: 26426067.

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The Costas Maranas Research group is not responsible if a program you download from this website does not work as expected.
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